Genetic Modification of Human Embryonic Stem Cells
نویسندگان
چکیده
منابع مشابه
Genetic modification of human embryonic stem cells.
Abbreviations: Ad: adenovirus, bFGF: basic fibroblast growth factor, BMP: bone morphogenetic protein, CNS: central nervous system, ES: embryonic stem, FACS: fluorescence activated cell sorting, HIV: human immunodeficiency virus, ICM: inner cell mass, LIF: leukemia inhibitory factor, MEF: mouse embryonic fibroblast, RNAi: RNA interference, SCNT: somatic cell nucleus transfer, UTR: untranslated r...
متن کاملGenome modification in human embryonic stem cells.
Induced pluripotent stem cell (iPSC) technology has emerged as the most promising method for generating patient-specific human embryonic stem (ES) cells and adult stem cells (Takahashi et al., 2007, Cell 131:861-872; Wernig et al., 2007, Nature 448:318-324; Park et al., 2008, Nature 451:141-146). So far, most studies of direct reprogramming have been done by using lentiviruses/retroviruses enco...
متن کاملDifferentiation of human embryonic stem cells into neurons
Human embryonic stem (ES) cells are undifferentiated pluripotent cells derived from the inner cell mass of blastocyst stage embryos. These unique cell lines have the potential to form virtually any cell type in the body and can be propagated in vitro indefinitely in an undifferentiated state. These cells are capable of forming embryoid bodies (EB) that contain cells from all three embryonic lin...
متن کاملDifferentiation of human embryonic stem cells into neurons
Human embryonic stem (ES) cells are undifferentiated pluripotent cells derived from the inner cell mass of blastocyst stage embryos. These unique cell lines have the potential to form virtually any cell type in the body and can be propagated in vitro indefinitely in an undifferentiated state. These cells are capable of forming embryoid bodies (EB) that contain cells from all three embryonic lin...
متن کاملReprogramming by cytosolic extract of human embryonic stem cells improves dopaminergic differentiation potential of human adipose tissue-derived stem cells
The extract of pluripotent stem cells induces dedifferentiation of somatic cells with restricted plasticity. In this study, we used the extract of human embryonic stem cells (hESC) to dedifferentiate adipose tissue-derived stem cells (ADSCs) and examined the impact of this reprogramming event on dopaminergic differentiation of the cells. For this purpose, cytoplasmic extract of ESCs was prepare...
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ژورنال
عنوان ژورنال: Biotechnology and Genetic Engineering Reviews
سال: 2007
ISSN: 0264-8725,2046-5556
DOI: 10.1080/02648725.2007.10648105